Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038458 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL196487 | 0.71 | KMT2A (0.70) | MEN1KMT2ATP53CYP2C19CYP2C9 | |
| SCHEMBL15038438 | 0.70 | CYP2C19 (0.40) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL202718 | 0.69 | MEN1 (0.61) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL17231390 | 0.67 | ALDH1A1 (0.55) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL22648480 | 0.66 | MEN1 (0.68) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL16544618 | 0.66 | MEN1 (0.68) | MEN1KMT2ATP53CYP2C19CYP2C9 | |
| SCHEMBL15038470 | 0.66 | KMT2A (0.58) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL11068784 | 0.66 | MEN1 (0.61) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL17231391 | 0.65 | CYP2C9 (0.72) | MEN1KMT2APLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604260-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |