Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812823 | 1.00 | TSHR (0.48) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25450869 | 0.83 | RCE1 (0.46) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19089919 | 0.83 | RCE1 (0.46) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1571975 | 0.81 | TSHR (0.52) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15003 | 0.81 | TSHR (0.52) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22156173 | 0.80 | AGXT (0.50) | IDO1CYP1A2AGXTTAAR1MAOA | |
| SCHEMBL2314025 | 0.79 | RCE1 (0.44) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20745824 | 0.79 | RCE1 (0.44) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| Ammonia Solution, Strong SCHEMBL21518155 | 0.79 | TSHR (0.50) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9504704 | 0.79 | TSHR (0.50) | TSHRIDO1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029576-B1 | CYCLOHEXYLIMIDAZOLE LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2013-06-19 | — | — | EP | disclosed |