Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044171 | 0.94 | ACHE (0.42) | ACHEMAOBRETAPPBCHE | |
| SCHEMBL301682 | 0.94 | ACHE (0.42) | ACHEMAOBRETAPPBCHE | |
| SCHEMBL303097 | 0.94 | ACHE (0.42) | ACHEMAOBRETAPPBCHE | |
| SCHEMBL29365202 | 0.94 | ACHE (0.42) | ACHEMAOBRETAPPBCHE | |
| SCHEMBL15040971 | 0.76 | MAOB (0.38) | MAOBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15040993 | 0.76 | MAOB (0.38) | MAOBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21098267 | 0.74 | CA1 (0.41) | ACHEMAOBLCKAPPMEN1 | |
| SCHEMBL12977425 | 0.73 | MAPT (0.53) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL12977423 | 0.73 | MAPT (0.53) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11871299 | 0.72 | HPGD (0.44) | MAOBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2023910-B1 | AH RECEPTOR ANTAGONISTS | SYMRISE AG (DE) | 2013-06-19 | — | — | EP | disclosed |