Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111037 | 0.91 | MAPT (0.54) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL10031355 | 0.88 | LIMK1 (0.47) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL3169910 | 0.83 | CYP1A2 (0.47) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL10371809 | 0.81 | CA2 (0.42) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL30414903 | 0.80 | KDM4E (0.48) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL204515 | 0.80 | KDM4E (0.48) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL15024214 | 0.80 | MAPT (0.51) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL10954079 | 0.80 | CA2 (0.41) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL10954796 | 0.80 | CA2 (0.41) | CA2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL7915404 | 0.79 | CYP1A2 (0.60) | MAPTHPGDALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |