Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016350 | 0.86 | MAPT (0.50) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15043386 | 0.81 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15043388 | 0.80 | HDAC6 (0.68) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL29988753 | 0.78 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15199000 | 0.78 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL2171116 | 0.78 | HDAC6 (0.48) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15436877 | 0.77 | HDAC1 (0.44) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL2171109 | 0.77 | HDAC6 (0.47) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL12388321 | 0.76 | NPC1 (0.50) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL10021006 | 0.76 | TNF (0.52) | HDAC6HDAC1HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | DR. REDDY'S LABORATORIES, INC. (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | FOLR1, FOLR2, FLT3 | HDAC6 2271/4885HDAC1 4097/4885HDAC3 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.