Sugi Predict
/ Targets
/ FOLR2
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to FOLR2 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer |
PHASE3 | ACTIVE_NOT_RECRUITING |
| A Study of Mirvetuximab Soravtansine vs. Investigator's Choice (IC) of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha (FRα) Expression |
PHASE3 | COMPLETED |
| How Precision Diets, Through Gut Bacteria, Affect Anemia in Nepalese Adolescent |
PHASE3 | NOT_YET_RECRUITING |
| Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer. |
PHASE2 | RECRUITING |
| A Placebo-controlled Trial of Folinic Acid in Children With ASD |
PHASE2 | RECRUITING |
| Study Using FolateScan to Identify Subjects With Folate Receptor-Positive Metastatic Renal Cell Carcinoma |
PHASE2 | COMPLETED |
| Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Safety and Efficacy of FolateScan (Technetium Tc 99m EC20) in Subjects With Suspected Metastatic Renal Cell Carcinoma |
PHASE2 | COMPLETED |
| A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer |
PHASE2 | RECRUITING |
| Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer |
PHASE2 | COMPLETED |
| Study of Vintafolide (MK-8109, EC145) in Participants With Advanced Ovarian and Endometrial Cancers (MK-8109-007, EC-FV-02) |
PHASE2 | COMPLETED |
| Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer |
PHASE2 | RECRUITING |
| Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer |
PHASE2 | COMPLETED |
| Intraoperative Imaging of Pulmonary Nodules by OTL38 |
PHASE1 | COMPLETED |
| [18F]-AZAFOL AS POSITRON EMISSION TOMOGRAPHY (PET) TRACER in FR Positive Cancer Imaging |
PHASE1 | COMPLETED |
| Study of EC0225 for the Treatment of Refractory or Metastatic Tumors |
PHASE1 | COMPLETED |
| Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers |
PHASE1 | COMPLETED |
| Study of EC0489 for the Treatment of Refractory or Metastatic Tumors |
PHASE1 | COMPLETED |
| Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS) |
PHASE1 | WITHDRAWN |
| Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer |
PHASE1 | COMPLETED |
| ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML |
PHASE1 | WITHDRAWN |
| The Development of Human Immunologic Assays Specific to Folate Receptor Antigen |
nan | UNKNOWN |
| Measurement of the Folate Receptor in Blood |
nan | COMPLETED |
| PK/PD Investigation of Calciumfolinat in Blood, Tumor and Adjacent Mucosa in Patient With Colon Cancer |
nan | UNKNOWN |
| DHFR 19 bp Deletion Polymorphism and Folic Acid Utilization |
nan | COMPLETED |
| Influence of Iron and Foliate Transporters on Bioavailability of These Micronutrients in the Organism |
nan | COMPLETED |
| Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies |
nan | RECRUITING |
| Assessing Colonic Folate Absorption & Metabolism |
nan | UNKNOWN |
| INAS-FOCUS (International Active Surveillance Study - Folate in Oral Contraceptives Utilization Study) |
nan | COMPLETED |
| Association of MSI, TS, DPD, MVD and EGFR With Chemosensitivity in Stage IV in Colorectal Cancer |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a FOLR2 binder may also engage these)