⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504344 | 1.00 | — | — | |
| SCHEMBL2251117 | 1.00 | — | — | |
| SCHEMBL15940330 | 0.88 | — | — | |
| SCHEMBL99597 | 0.88 | — | — | |
| SCHEMBL99596 | 0.88 | — | — | |
| SCHEMBL2253136 | 0.88 | — | — | |
| SCHEMBL2253133 | 0.88 | — | — | |
| SCHEMBL101534 | 0.88 | — | — | |
| SCHEMBL521914 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL521913 | 0.86 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912979-B1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC (US) | 2026-03-25 | — | — | EP | claimed |
| CN-117810530-A | In-situ polymerization high-voltage-resistant semi-solid electrolyte, preparation method thereof and lithium metal semi-solid battery | 四川启睿克科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117410439-A | Electrode plate, preparation method thereof and battery | 蜂巢能源科技股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| EP-4138836-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND OTHER DISORDERS INVOLVING CYTOKINE STORM USING BTK INHIBITORS | Principia Biopharma Inc. (US) | 2023-03-01 | — | — | EP | claimed |
| CN-115443136-A | Treatment of acute respiratory distress syndrome and other disorders involving cytokine storm using BTK inhibitors | 普林斯匹亚生物制药公司 | 2022-12-06 | — | — | CN | claimed |
| EP-3478687-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | Daewoong Pharmaceutical Co., Ltd. (KR) | 2019-05-08 | — | — | EP | claimed |
| WO-2018004306-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-01-04 | — | — | WO | claimed |
| EP-2861599-A1 | REVERSIBLE COVALENT PYRROLO- OR PYRAZOLOPYRIMIDINES USEFUL FOR THE TREATMENT CANCER AND AUTOIMMUNE DISEASES | Principia Biopharma Inc. (US) | 2015-04-22 | — | — | EP | claimed |
| EP-2710005-A1 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. (US) | 2014-03-26 | — | — | EP | claimed |
| WO-2013191965-A1 | REVERSIBLE COVALENT PYRROLO- OR PYRAZOLOPYRIMIDINES USEFUL FOR THE TREATMENT CANCER AND AUTOIMMUNE DISEASES | PRINCIPIA BIOPHARMA INC. (US) | 2013-12-27 | — | — | WO | claimed |
| WO-2012158764-A1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | claimed |
| US-20110207835-A1 | Alpha, Beta, Unsaturated Nitriles as Fragrances | GIVAUDAN SA (CH) | 2011-08-25 | — | — | US | claimed |
| EP-2079436-B1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2010-11-10 | — | — | EP | claimed |
| CN-101516324-A | Alpha, beta-unsaturated nitriles as fragrances | GIVAUDAN SA (CH) | 2009-08-26 | — | — | CN | claimed |
| EP-2079436-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | Givaudan SA (CH) | 2009-07-22 | — | — | EP | claimed |
| WO-2008037105-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2008-04-03 | — | — | WO | claimed |
| US-20250340559-A1 | PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS | INCYTE HOLDINGS CORP (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250243183-A1 | IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS | INCYTE CORPORATION | 2025-07-31 | — | — | US | disclosed |
| EP-0038575-B1 | CYANOVINYL-CYCLOPROPANECARBOXYLIC ACIDS AND METHOD OF PREPARING THESE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| EP-0038575-A2 | Cyanovinyl-cyclopropanecarboxylic acids and method of preparing these compounds | AMERICAN CYANAMID COMPANY (US) | 1981-10-28 | — | — | EP | disclosed |