SCHEMBL15043590

SCHEMBL15043590

C=COCc1ccc(C2CCC(C)CC2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12242825 0.85 ESR2 (0.35) ESR2
SCHEMBL802712 0.82 ESR2 (0.33) ESR2
SCHEMBL18722013 0.80 ADRA1A (0.35) ESR2
SCHEMBL12733657 0.80 ADRA1A (0.35) ESR2
SCHEMBL30856 0.80 ESR2 (0.34) ESR2
SCHEMBL803207 0.78 KDM4E (0.31)
SCHEMBL17615972 0.77 ESR2 (0.34) ESR2
SCHEMBL12716064 0.77 ESR2 (0.34) ESR2
SCHEMBL12719836 0.76 ESR2 (0.43) ESR2
SCHEMBL12736617 0.76 HTR2C (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9617473-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2017-04-11 US disclosed
US-20130155338-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-20 US disclosed