Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 6/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441627 | 0.89 | CACNA1B (0.50) | CACNA1BAPBA1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL15444037 | 0.89 | CACNA1B (0.50) | CACNA1BAPBA1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL15043597 | 0.89 | CACNA1B (0.50) | CACNA1BAPBA1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL24728884 | 0.82 | CACNA1B (0.44) | CACNA1BAPBA1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL19857280 | 0.82 | CACNA1B (0.44) | CACNA1BAPBA1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL15043612 | 0.82 | CACNA1B (0.53) | CACNA1BAPBA1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL15043607 | 0.81 | CACNA1B (0.49) | CACNA1BAPBA1SMN1; SMN2CNR2ALDH1A1 | |
| SCHEMBL31722261 | 0.79 | PTGS1 (0.50) | CACNA1BAPBA1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL15431833 | 0.78 | CACNA1B (0.46) | CACNA1BAPBA1ALDH1A1HSD17B10LMNA | |
| SCHEMBL15043600 | 0.77 | KDM4E (0.49) | CACNA1BAPBA1SMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | NSUN2, POLL, NT5C3B | CACNA1B 2908/4885APBA1 1172/4885SMN1; SMN2 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.