Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.57 |
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591539 | 0.82 | DRD3 (0.58) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL3312231 | 0.81 | DRD2 (0.57) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL14154264 | 0.81 | DRD3 (0.57) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL563307 | 0.77 | RAD52 (0.79) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL21146544 | 0.77 | DRD3 (0.53) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL24061285 | 0.77 | DRD3 (0.56) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL9574602 | 0.76 | RAD52 (0.50) | DRD3DRD2MAPTADRA2ALMNA | |
| SCHEMBL114205 | 0.76 | RAD52 (0.63) | DRD3DRD2MAPTADRA2ALMNA | |
| Hydrochloric Acid SCHEMBL10652670 | 0.75 | RAD52 (0.77) | DRD3DRD2MAPTADRA2ALMNA | |
| Bromide SCHEMBL1253502 | 0.74 | RAD52 (0.61) | DRD3DRD2MAPTADRA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087807-A1 | 4-ARYL IMIDAZOLE DERIVATIVES AS MGLU5 POSITIVE ALLESTERIC MODIULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |