Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055358 | 1.00 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22822298 | 1.00 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27654640 | 0.81 | CAD (0.55) | TSHRALDH1A1HPGDCAD | |
| SCHEMBL11664935 | 0.81 | CA14 (0.52) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4103383 | 0.80 | CA14 (0.46) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22688557 | 0.80 | CA12 (0.42) | CA14MEN1KMT2AMAPTRECQL | |
| SCHEMBL21549703 | 0.80 | CA12 (0.42) | CA14MEN1KMT2AMAPTRECQL | |
| SCHEMBL22266570 | 0.79 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1884920 | 0.79 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15561530 | 0.79 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089212-A1 | SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2013-06-20 | — | — | WO | disclosed |