⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14191772 | 0.79 | — | — | |
| SCHEMBL18630077 | 0.79 | — | — | |
| SCHEMBL2014044 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL2011969 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL2011964 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL7946995 | 0.70 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL6548023 | 0.69 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL486427 | 0.68 | — | — | |
| SCHEMBL12240486 | 0.68 | — | — | |
| SCHEMBL12240470 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-08 | — | — | US | disclosed |
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-15 | — | — | US | disclosed |
| US-9512073-B2 | Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20130158021-A1 | AMINO ACID-, PEPTIDE-AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-20 | — | — | US | disclosed |