Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014044 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA9 | |
| SCHEMBL2011969 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA9 | |
| SCHEMBL2011964 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA9 | |
| SCHEMBL4000984 | 0.72 | SIGMAR1 (0.44) | SMN1; SMN2 | |
| SCHEMBL4745932 | 0.72 | SIGMAR1 (0.44) | SMN1; SMN2 | |
| SCHEMBL8403262 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9 | |
| SCHEMBL11654410 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9 | |
| SCHEMBL15044683 | 0.70 | — | — | |
| SCHEMBL15388299 | 0.67 | PLA2G10 (0.39) | SMN1; SMN2 | |
| SCHEMBL29946367 | 0.67 | PDK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011367-A2 | BIMODAL LIGANDS WITH MACROCYCLIC AND ACYCLIC BINDING MOIETIES, COMPLEXES AND COMPOSITIONS THEREOF, AND METHODS OF USING | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2010-01-28 | — | — | WO | disclosed |