Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16173873 | 1.00 | MAPT (0.41) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL16173871 | 0.93 | MAPT (0.39) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL15044906 | 0.93 | MAPT (0.39) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL16170784 | 0.93 | MAPT (0.39) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL15044914 | 0.91 | MAPT (0.38) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL15044922 | 0.89 | CA2 (0.41) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL15044902 | 0.89 | CA2 (0.41) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL16173874 | 0.89 | CA2 (0.41) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL16173869 | 0.89 | CA2 (0.41) | MAPTNPSR1ALDH1A1GAAGFER | |
| SCHEMBL15044692 | 0.86 | MAPT (0.39) | MAPTNPSR1ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961621-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140304926-A1 | Azo Dyes | HUNTSMAN INTERNATIONAL LLC | 2014-10-16 | — | — | US | disclosed |
| WO-2013087400-A2 | AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2013-06-20 | — | — | WO | disclosed |