Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719880 | 0.83 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28488125 | 0.77 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL2539106 | 0.75 | — | — | |
| SCHEMBL9152549 | 0.75 | — | — | |
| SCHEMBL16440972 | 0.75 | — | — | |
| SCHEMBL1504625 | 0.74 | — | — | |
| SCHEMBL7771328 | 0.73 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL599552 | 0.73 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL599554 | 0.73 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL27622701 | 0.72 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155683-B8 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-2155683-B1 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-03-16 | — | — | EP | disclosed |