Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655977 | 1.00 | DPP4 (0.43) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL15045201 | 0.89 | DPP4 (0.49) | DPP4DPP7DPP8DPP9SMYD3 | |
| SCHEMBL739765 | 0.86 | PDE4B (0.44) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL22000200 | 0.86 | PDE4B (0.44) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL27405335 | 0.86 | PDE4B (0.44) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL12521649 | 0.84 | PDE9A (0.40) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL17308198 | 0.84 | PDE9A (0.40) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL16132288 | 0.84 | PDE9A (0.40) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL17308197 | 0.84 | PDE9A (0.40) | DPP4DPP7DPP8DPP9PDE9A | |
| SCHEMBL17308204 | 0.84 | PDE9A (0.40) | DPP4DPP7DPP8DPP9PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |