Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655977 | 0.89 | DPP4 (0.43) | DPP4DPP7SMYD3FAPPREP | |
| SCHEMBL15045183 | 0.89 | DPP4 (0.43) | DPP4DPP7SMYD3FAPPREP | |
| SCHEMBL19981628 | 0.86 | DPP4 (0.47) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL738191 | 0.85 | KMT2A (0.44) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL12521996 | 0.83 | KMT2A (0.43) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL10328343 | 0.83 | KMT2A (0.43) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL8690808 | 0.82 | MEN1 (0.40) | DPP4DPP7SMYD3MEN1ALDH1A1 | |
| SCHEMBL17152626 | 0.82 | DPP4 (0.47) | DPP4DPP7KMT2ADPP8DPP9 | |
| SCHEMBL12522241 | 0.81 | HPGD (0.44) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL8690804 | 0.80 | SMYD3 (0.38) | DPP4DPP7SMYD3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |