Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | GJB2 | P29033 | 5/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413946 | 0.92 | GBA1 (0.44) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL12353567 | 0.90 | GBA1 (0.47) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL15976021 | 0.90 | GBA1 (0.47) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL13166628 | 0.90 | GBA1 (0.47) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL15976022 | 0.87 | TNF (0.38) | TNFGBA1MAPK1 | |
| SCHEMBL12336991 | 0.87 | GBA1 (0.47) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL14714134 | 0.87 | GBA1 (0.47) | TNFGBA1GJB2MGAMSI | |
| SCHEMBL17371173 | 0.85 | TNF (0.40) | TNFGBA1 | |
| SCHEMBL12670465 | 0.85 | TNF (0.40) | TNFGBA1 | |
| SCHEMBL15304397 | 0.85 | TNF (0.40) | TNFGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158242-A1 | ALPHA-SELECTIVE GLYCOSYLATION METHOD | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158242-A1 | ALPHA-SELECTIVE GLYCOSYLATION METHOD | SI, OGA, ALG8 | TNF 1884/4885GBA1 45/4885GJB2 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.