SCHEMBL1504574

SCHEMBL1504574

CS(=O)(=O)NCCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582338 0.83
SCHEMBL3043384 0.81 POLB (0.44)
SCHEMBL12090531 0.75 POLB (0.52)
SCHEMBL10794496 0.75 CA1 (0.50)
SCHEMBL147224 0.75
SCHEMBL28028355 0.74
SCHEMBL14739086 0.73 GRIA1 (0.52)
SCHEMBL14739265 0.73 GRIA1 (0.52)
SCHEMBL14739515 0.73 GRIA1 (0.52)
SCHEMBL2112171 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210299-A METHOD FOR PRODUCTION OF N-(2-CHLOROETHYL) METHANESULFONAMIDE NIPPON SHOKUBAI CO., LTD. (JP) 1993-05-11 US claimed
US-4505859-A Preparation of 2-haloethylamides THE DOW CHEMICAL COMPANY (US) 1985-03-19 US claimed
JP-5032611-A None JP disclosed
JP-4221361-A None JP disclosed
JP-4221360-A None JP disclosed
US-12404269-B2 Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof ZHEJIANG UNIVERSITY (CN) 2025-09-02 US disclosed
WO-2025056065-A1 CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE 上海医药集团股份有限公司 2025-03-20 WO disclosed
CN-119638669-A Chemokine receptor antagonist, pharmaceutical composition and application 上海医药集团股份有限公司 2025-03-18 CN disclosed
US-20220017505-A1 AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2022-01-20 US disclosed
EP-3904343-A1 AMINO QUINAZOLINONE, AMINO ISOQUINOLONE DERIVATIVES AND APPLICATION THEREOF Zhejiang University (CN) 2021-11-03 EP disclosed
WO-2020134921-A1 AMINO QUINAZOLINONE, AMINO ISOQUINOLONE DERIVATIVES AND APPLICATION THEREOF 浙江大学 2020-07-02 WO disclosed
JP-H04221361-A SULFONAMIDE DERIVATIVE FUJI PHOTO FILM CO LTD 1992-08-11 JP disclosed
JP-H04221360-A SULFONAMIDE DERIVATIVE FUJI PHOTO FILM CO LTD 1992-08-11 JP disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
US-4505859-A Preparation of 2-haloethylamides THE DOW CHEMICAL COMPANY (US) 1985-03-19 US disclosed
US-4265825-A BY REACTING AN ALKANOL AND N-(HALOALKYL) SULFONYL IMIDE THE DOW CHEMICAL COMPANY (US) 1981-05-05 US disclosed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4009205-A PROCESS FOR PREPARING 4-AMINO-3-METHYL-N-SUBSTITUTED OR UNSUBSTITUTED ALKYLANILINES SANKO CHEMICAL COMPANY LTD. (JA) 1977-02-22 US disclosed
US-3956385-A REACTING SULFONYLHALIDE WITH 2-CHLORO-ETHYLAMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-11 US disclosed