SCHEMBL3043384

SCHEMBL3043384

CS(=O)(=O)NCCNS(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
ALDH1A1 P00352 5/20 0.41
MAPT P10636 2/20 0.41
CA2 P00918 2/20 0.41
CA1 P00915 2/20 0.40
ALOX15 P16050 1/20 0.40
RECQL P46063 2/20 0.39
NQO2 P16083 1/20 0.39
CA12 O43570 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
HTT P42858 1/20 0.36
KDM4D Q6B0I6 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1908710 0.87
SCHEMBL12090531 0.86 POLB (0.52) POLBALDH1A1MAPTCA2CA1
SCHEMBL147224 0.86
SCHEMBL3421764 0.85
Hydrochloric Acid SCHEMBL16990399 0.85 POLB (0.38) POLBALDH1A1MAPTCA2CA1
SCHEMBL19303352 0.85 POLB (0.38) POLBALDH1A1MAPTCA2CA1
SCHEMBL14739086 0.83 GRIA1 (0.52) POLBALDH1A1CA2CA1CA12
SCHEMBL14739265 0.83 GRIA1 (0.52) POLBALDH1A1CA2CA1CA12
SCHEMBL14740061 0.83 GRIA1 (0.52) POLBALDH1A1CA2CA1CA12
SCHEMBL736693 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213793-B1 SULPHONAMIDES JOHN WYETH & BROTHER LIMITED (GB) 1992-03-18 EP claimed
CN-111403809-B Additive for lithium secondary battery, electrolyte and lithium secondary battery comprising same 三星SDI株式会社 2023-08-18 CN disclosed
US-11329318-B2 Electrolyte additive for lithium secondary battery and lithium secondary battery including the same SAMSUNG SDI CO., LTD. (KR) 2022-05-10 US disclosed
CN-111403809-A Additive for lithium secondary battery, electrolyte and lithium secondary battery comprising same 三星SDI株式会社 2020-07-10 CN disclosed
US-20200220217-A1 ELECTROLYTE ADDITIVE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-07-09 US disclosed
WO-2018152438-A1 AMINE-APPENDED METAL-ORGANIC FRAMEWORKS EXHIBITING A NEW ADSORPTION MECHANISM FOR CARBON DIOXIDE SEPARATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-08-23 WO disclosed
US-20140176653-A1 NOVEL COMPOUND HAVING MULTIMER STRUCTURE OF XANTHENE DERIVATIVE, COLORING COMPOSITION, INK FOR INKJET RECORDING, METHOD OF INKJET RECORDING, COLOR FILTER, AND COLOR TONER FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
WO-2014075648-A1 A METHOD OF PREPARING APIXABAN ZENTIVA, K.S. (CZ) 2014-05-22 WO disclosed
US-8563679-B2 Catalytic systems for the ring-opening (co)polymerization of lactones IPSEN PHARMA S.A.S. (FR) 2013-10-22 US disclosed
US-8440417-B2 Method for assaying compounds or agents for ability to displace potent ligands of hematopoietic prostaglandin D synthase CAYMAN CHEMICAL COMPANY, INCORPORATED (US) 2013-05-14 US disclosed
US-20110054144-A1 NOVEL CATALYTIC SYSTEMS FOR THE RING-OPENING (CO)POLYMERIZATION OF LACTONES IPSEN PHARMA S.A.S. (FR) 2011-03-03 US disclosed
US-7763747-B2 Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; Alzheimer's disease; diabetes; A beta amyloidosis PROTEOTECH, INC. (US) 2010-07-27 US disclosed
WO-2009138589-A1 NOVEL CATALYTIC SYSTEMS FOR THE RING-OPENING (CO)POLYMERIZATION OF LACTONES IPSEN PHARMA S.A.S. (FR) 2009-11-19 WO disclosed
WO-2009140364-A2 METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE CAYMAN CHEMICAL COMPANY (US) 2009-11-19 WO disclosed
US-20090069432-A1 Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; Alzheimer's disease; diabetes; A beta amyloidosis PROTEOTECH INC. 2009-03-12 US disclosed
WO-2007091950-A1 BENZIMIDAZOLES AND IMIDAZOPYRIDINES USEFUL IN THE TREATMENT OF DISEASES OR DISORDERS ASSOCIATED WITH CANNABINOID RECEPTOR 2 (CB2) SUCH AS PAIN ASTRAZENECA AB (SE) 2007-08-16 WO disclosed
EP-1713796-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS CO., LTD. (KR) 2006-10-25 EP disclosed
WO-2005077942-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS, CO., LTD. (KR) 2005-08-25 WO disclosed
WO-1992012187-A1 CHIRAL POLYMERS, THEIR PREPARATION AND USE IN PREPARING OPTICALLY ACTIVE PROPIONIC 2-ARYL ACIDS RHONE-POULENC RORER S.A. (FR) 1992-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054144-A1 NOVEL CATALYTIC SYSTEMS FOR THE RING-OPENING (CO)POLYMERIZATION OF LACTONES COASY, STS, SQOR POLB 1336/4885ALDH1A1 1772/4885MAPT 3312/4885
US-20200220217-A1 ELECTROLYTE ADDITIVE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME SLC26A3, SLC9A1, SLC9B2 POLB 203/4885ALDH1A1 244/4885MAPT 1525/4885
US-11329318-B2 Electrolyte additive for lithium secondary battery and lithium secondary battery including the same SLC26A3, SLC9A1, SLC9B2 POLB 203/4885ALDH1A1 244/4885MAPT 1525/4885
US-20090069432-A1 Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; Alzheimer's disease; diabetes; A beta amyloidosis IAPP, APP, SNCA POLB 1672/4885ALDH1A1 2505/4885MAPT 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.