Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001854 | 0.81 | STING1 (0.41) | STING1PDE2ATAS1R3TAS1R1 | |
| SCHEMBL15257768 | 0.78 | PDE2A (0.44) | STING1PDE2ATAS1R3TAS1R1 | |
| SCHEMBL19370325 | 0.78 | STING1 (0.39) | STING1PDE2ATAS1R3TAS1R1 | |
| SCHEMBL18870640 | 0.73 | STING1 (0.36) | STING1PDE2A | |
| SCHEMBL12594003 | 0.70 | PDE2A (0.37) | STING1PDE2AHBBHSD17B10TAS1R3 | |
| SCHEMBL16127107 | 0.70 | PDE2A (0.40) | STING1PDE2ATAS1R3TAS1R1 | |
| SCHEMBL17928575 | 0.69 | STING1 (0.32) | STING1 | |
| SCHEMBL18858878 | 0.69 | STING1 (0.34) | STING1PDE2A | |
| SCHEMBL14185047 | 0.69 | PDE2A (0.43) | STING1PDE2AALDH1A1 | |
| SCHEMBL16125297 | 0.68 | PDE2A (0.36) | STING1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090420-A2 | FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |