SCHEMBL18870640

SCHEMBL18870640

CN1C(=O)C=NC2C(=O)NC(N)=NC21

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.36
PDE2A O00408 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18858878 0.82 STING1 (0.34) STING1PDE2A
SCHEMBL14001854 0.79 STING1 (0.41) STING1PDE2A
SCHEMBL17928575 0.78 STING1 (0.32) STING1
SCHEMBL15045875 0.73 STING1 (0.42) STING1PDE2A
SCHEMBL19370325 0.72 STING1 (0.39) STING1PDE2A
SCHEMBL15257768 0.72 PDE2A (0.44) STING1PDE2A
SCHEMBL24140234 0.70 STING1 (0.31) STING1
SCHEMBL14185047 0.67 PDE2A (0.43) STING1PDE2A
SCHEMBL16127107 0.65 PDE2A (0.40) STING1PDE2A
SCHEMBL15869925 0.63 PDE2A (0.32) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 STING1 205/4885PDE2A 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.