Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 10/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681100 | 0.85 | CTSK (0.43) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL1503591 | 0.83 | CTSK (0.42) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL1504753 | 0.82 | POLB (0.47) | CTSLALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL1503616 | 0.81 | CTSK (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL1504675 | 0.81 | PREP (0.37) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL1504923 | 0.80 | POLB (0.49) | CTSKCTSSKMT2A | |
| SCHEMBL995279 | 0.75 | MEN1 (0.41) | CTSKCTSSALDH1A1KDM4ETSHR | |
| SCHEMBL995280 | 0.75 | MEN1 (0.41) | CTSKCTSSALDH1A1KDM4ETSHR | |
| SCHEMBL18857996 | 0.70 | CTSK (0.41) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL14392535 | 0.70 | CTSK (0.43) | CA1CA2CA7CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033009-A1 | N- [2-HYDROXYCARBAMOYL-2- (PIPERAZINYL) ETHYL] BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-03-24 | — | — | WO | disclosed |