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Sugi Predict / Compounds / SCHEMBL15046214

SCHEMBL15046214

SCHEMBL15046214

CC1(C)c2cc(Nc3ccccc3)ccc2-c2ccc(-c3ccc(-c4ccc5c(c4)C(C)(C)c4cc6c(cc4-5)C(C)(C)c4ccccc4N6c4ccccc4)cc3)cc21

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 2/20 0.41
▸ PDK2 Q15119 3/20 0.38
▸ GNG2 P59768 1/20 0.35
▸ GNB1 P62873 1/20 0.35
▸ APP P05067 1/20 0.33
▸ MARK3 P27448 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ GFER P55789 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15046206 0.99 PGR (0.41) PGRPDK2GNG2GNB1APP
SCHEMBL15046204 0.93 PGR (0.46) PGRPDK2GNG2GNB1APP
SCHEMBL15046209 0.93 PGR (0.37) PGRPDK2GNG2GNB1APP
SCHEMBL15046242 0.88 PGR (0.35) PGRPDK2
SCHEMBL15046325 0.88 PGR (0.35) PGRPDK2
SCHEMBL15019833 0.84 PGR (0.36) PGRPDK2MEN1KMT2A
SCHEMBL19042757 0.84 PDK2 (0.39) PGRPDK2MEN1KMT2A
SCHEMBL16900616 0.84 PGR (0.40) PGRPDK2MEN1KMT2A
SCHEMBL24969755 0.84 PGR (0.38) PGRPDK2GNG2GNB1APP
SCHEMBL16900626 0.84 PGR (0.42) PGRPDK2MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013089460-A1 NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME 주식회사 두산 (KR) 2013-06-20 — — WO disclosed
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