Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046355 | 0.92 | NR1H2 (0.39) | NR1H3NR1H2HTTPOLBPDK2 | |
| SCHEMBL15046420 | 0.90 | NR1H2 (0.40) | NR1H3NR1H2HTTPOLBPDK2 | |
| SCHEMBL15046228 | 0.90 | PGR (0.38) | NR1H3HTTPOLBPDK2PGR | |
| SCHEMBL15118493 | 0.88 | NR1H2 (0.38) | NR1H3NR1H2HTTPOLBPGR | |
| SCHEMBL15046396 | 0.86 | PTPN1 (0.35) | NR1H3HTTPOLBPDK2PGR | |
| SCHEMBL15046421 | 0.86 | NR1H2 (0.33) | NR1H3NR1H2 | |
| SCHEMBL16940893 | 0.86 | ITGB2 (0.39) | NR1H3HTTPGRMAPTMEN1 | |
| SCHEMBL15118492 | 0.86 | ITGB2 (0.36) | NR1H3NR1H2PGRKMT2ANPSR1 | |
| SCHEMBL15046239 | 0.85 | NR1H2 (0.39) | NR1H3NR1H2TRPV1PDK2ESR1 | |
| SCHEMBL15046250 | 0.85 | NR1H2 (0.39) | NR1H3NR1H2TRPV1PDK2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089460-A1 | NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME | 주식회사 두산 (KR) | 2013-06-20 | — | — | WO | disclosed |