Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047332 | 0.80 | — | — | |
| SCHEMBL27773768 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL1614031 | 0.72 | TSHR (0.35) | TSHR | |
| SCHEMBL19068813 | 0.72 | TSHR (0.35) | TSHR | |
| SCHEMBL15047286 | 0.70 | — | — | |
| SCHEMBL25756932 | 0.70 | TSHR (0.33) | TSHR | |
| SCHEMBL11427882 | 0.70 | — | — | |
| SCHEMBL15142387 | 0.70 | — | — | |
| SCHEMBL132888 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL28370183 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045511-B2 | Supported ligands having a high local density of coordinating atoms | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-06-02 | — | — | US | disclosed |
| US-20130158219-A1 | SUPPORTED LIGANDS HAVING A HIGH LOCAL DENSITY OF COORDINATING ATOMS | UNIVERSITE DE BOURGOGNE (FR) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158219-A1 | SUPPORTED LIGANDS HAVING A HIGH LOCAL DENSITY OF COORDINATING ATOMS | SLC40A1, FECH, IDH2 | TSHR 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.