⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959546 | 0.73 | — | — | |
| SCHEMBL9328781 | 0.73 | — | — | |
| SCHEMBL10533446 | 0.73 | — | — | |
| SCHEMBL16969922 | 0.71 | — | — | |
| SCHEMBL11173848 | 0.69 | — | — | |
| SCHEMBL6414112 | 0.69 | FDPS (0.39) | — | |
| SCHEMBL16969836 | 0.69 | — | — | |
| SCHEMBL11388928 | 0.67 | — | — | |
| SCHEMBL10470535 | 0.67 | — | — | |
| SCHEMBL1708069 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-4289712-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-09-15 | — | — | US | claimed |
| US-4247489-A | Process for preparing tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-01-27 | — | — | US | claimed |
| US-4207272-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1980-06-10 | — | — | US | claimed |
| US-8173684-B2 | Pyridone derivatives as p38α MAPK inhibitors | ASTELLAS PHARMA INC. (JP) | 2012-05-08 | — | — | US | disclosed |
| EP-2155683-B8 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-2155683-B1 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20100063098-A1 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-2155683-A2 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | Astellas Pharma Inc. (JP) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008140066-A2 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2008-11-20 | — | — | WO | disclosed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
| US-7256211-B1 | 8-azaprostaglandin derivatives and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-4289712-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4289712-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4247489-A | Process for preparing tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| US-4247489-A | Process for preparing tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| US-4247489-A | Process for preparing tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| US-4207272-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4207272-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4207272-A | Tetrachloro-butyl secondary phosphites | OLIN CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |