SCHEMBL1504770

SCHEMBL1504770

CCC(=NOC)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O)CC(O)C(C)C(OC(C)=O)/C=C/C1C

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625445 0.86 SF3B3 (0.61) SF3B3
SCHEMBL13503233 0.84 SF3B3 (0.63) SF3B3
SCHEMBL3552260 0.84 SF3B3 (0.63) SF3B3
SCHEMBL3626035 0.77 SF3B3 (0.65) SF3B3
SCHEMBL12834259 0.76 SF3B3 (0.49) SF3B3
SCHEMBL371282 0.76 SF3B3 (0.69) SF3B3
SCHEMBL1505060 0.76 SF3B3 (0.58) SF3B3
SCHEMBL13503234 0.76 SF3B3 (0.58) SF3B3
SCHEMBL1505084 0.75 SF3B3 (0.44) SF3B3
SCHEMBL1504984 0.74 SF3B3 (0.43) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292610-A1 Macrolides with VEGF transcription suppression activity MERCIAN CORPORATION (JP) 2011-03-09 EP disclosed