Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 6/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 5/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925240 | 1.00 | DRD1 (0.45) | DRD1PPIDSIRT6SIRT1SIRT5 | |
| SCHEMBL3925234 | 1.00 | DRD1 (0.45) | DRD1PPIDSIRT6SIRT1SIRT5 | |
| SCHEMBL5366976 | 0.89 | SIRT6 (0.43) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL5812127 | 0.87 | SIRT6 (0.43) | PPIDSIRT6SIRT1SIRT5NPY4R | |
| SCHEMBL5812133 | 0.87 | SIRT6 (0.43) | PPIDSIRT6SIRT1SIRT5NPY4R | |
| SCHEMBL3935159 | 0.87 | NPY4R (0.44) | PPIDMETAP2METAP1NPY4RNPY1R | |
| SCHEMBL3928619 | 0.86 | FNTA (0.47) | SIRT5 | |
| SCHEMBL31279889 | 0.86 | FNTA (0.47) | SIRT5 | |
| SCHEMBL6757012 | 0.85 | SIRT6 (0.39) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL752327 | 0.85 | DRD1 (0.50) | DRD1PPIDMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325735-B1 | Use of L-arginine derivatives as photo-protecting agents and enhancing melanic response in cosmetic compositions | EXSYMOL SA (MC) | 2013-06-19 | — | — | EP | disclosed |