Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047968 | 0.89 | KIT (0.31) | KIT | |
| SCHEMBL15047992 | 0.86 | KIT (0.31) | KIT | |
| SCHEMBL15047971 | 0.82 | FGFR1 (0.34) | — | |
| SCHEMBL15023001 | 0.80 | KIT (0.31) | KIT | |
| SCHEMBL15047901 | 0.76 | FGFR1 (0.36) | — | |
| SCHEMBL15047972 | 0.72 | TNK2 (0.30) | — | |
| SCHEMBL15047967 | 0.72 | KIT (0.44) | KIT | |
| SCHEMBL15046129 | 0.72 | KIT (0.32) | KIT | |
| SCHEMBL22132829 | 0.69 | LMNA (0.37) | — | |
| SCHEMBL15023008 | 0.68 | KIT (0.31) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087578-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-20 | — | — | WO | disclosed |