Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.82 |
| ▸ | CCR5 | P51681 | 6/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14011061 | 1.00 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL3326125 | 1.00 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL18901440 | 1.00 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL13627660 | 0.90 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL3322708 | 0.90 | CCR2 (0.79) | CCR2KCNH2CCR5 | |
| SCHEMBL14011062 | 0.90 | CCR2 (0.79) | CCR2KCNH2CCR5 | |
| SCHEMBL3987100 | 0.90 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL4146068 | 0.90 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL13335024 | 0.89 | CCR2 (0.66) | CCR2KCNH2CCR5 | |
| SCHEMBL3325003 | 0.89 | CCR2 (0.66) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | claimed |
| EP-1763351-B1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2016-11-30 | — | — | EP | claimed |
| US-8470827-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2013-06-25 | — | — | US | claimed |