SCHEMBL15048865

SCHEMBL15048865

CCCCCCSSC(=S)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.61
ALDH1A1 P00352 7/20 0.59
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
ALDH2 P05091 3/20 0.43
CNR2 P34972 1/20 0.41
KCNH2 Q12809 1/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.38
EPHX2 P34913 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28334233 1.00 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23603108 1.00 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL22749487 1.00 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29132907 1.00 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29132928 1.00 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29132882 0.99 MGLL (0.63) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL22749379 0.94 MGLL (0.65) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23927811 0.93 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL21947395 0.93 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23927812 0.93 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287290-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2024-08-29 US claimed
CN-115850821-A Special inner support rubber composition for run-flat tire and preparation method thereof 青岛双星轮胎工业有限公司 2023-03-28 CN claimed
CN-113736208-A Rubber composition, preparation method thereof and run-flat tire inner support 青岛双星轮胎工业有限公司 2021-12-03 CN claimed
CN-112430204-A 1, 6-bis (N, N' -dibenzyl thiocarbamoyl disulfide) hexane as anti-reversion agent and preparation method thereof 江苏麒祥高新材料有限公司 2021-03-02 CN claimed
US-20250197614-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2025-06-19 US disclosed
US-20240287290-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2024-08-29 US disclosed
US-20240199859-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2024-06-20 US disclosed
CN-113993719-B Trisulfide compound 住友化学株式会社 2024-01-02 CN disclosed
US-20230167279-A1 CORROSION RESISTANCE OF RUBBER-BASED ADHESIVES AND SEALANTS HENKEL AG & CO KGAA (DE) 2023-06-01 US disclosed
CN-115850821-A Special inner support rubber composition for run-flat tire and preparation method thereof 青岛双星轮胎工业有限公司 2023-03-28 CN disclosed
CN-111662482-B Vulcanizing agent composition, composition for preparing rubber compound, rubber compound and preparation method thereof, and tire 华奇(中国)化工有限公司 2022-07-26 CN disclosed
CN-113939559-A Tyre for vehicle wheels 住友橡胶工业株式会社 2022-01-14 CN disclosed
WO-2020162304-A1 RUBBER COMPOSITION AND TIRE 住友ゴム工業株式会社 2020-08-13 WO disclosed
EP-3231839-B1 DAMPING-IMPARTING COMPOSITION HAVING HIGH IMPACT DURABILITY AT LOW TEMPERATURE HENKEL AG & CO KGAA (DE) 2020-02-19 EP disclosed
CN-110551328-A Pneumatic tire SUMITOMO RUBBER IND 2019-12-10 CN disclosed
US-10308791-B2 Damping-imparting composition having high impact durability at low temperature HENKEL AG & CO. KGAA (DE) 2019-06-04 US disclosed
EP-3231839-A1 DAMPING-IMPARTING COMPOSITION HAVING HIGH IMPACT DURABILITY AT LOW TEMPERATURE Henkel AG & Co. KGaA (DE) 2017-10-18 EP disclosed
US-20170267842-A1 DAMPING-IMPARTING COMPOSITION HAVING HIGH IMPACT DURABILITY AT LOW TEMPERATURE TOYOTA MOTOR CORPORATION (JP) 2017-09-21 US disclosed
EP-2607100-B1 Tire rubber composition GOODYEAR TIRE & RUBBER (US) 2014-10-01 EP disclosed
EP-2607100-A1 Tire rubber composition The Goodyear Tire & Rubber Company (US) 2013-06-26 EP disclosed