⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024 | 0.83 | — | — | |
| SCHEMBL2384 | 0.71 | — | — | |
| SCHEMBL32690450 | 0.69 | — | — | |
| SCHEMBL31675861 | 0.67 | — | — | |
| SCHEMBL29993421 | 0.67 | — | — | |
| SCHEMBL128941 | 0.67 | — | — | |
| SCHEMBL6276848 | 0.67 | — | — | |
| SCHEMBL7637912 | 0.67 | — | — | |
| SCHEMBL22434925 | 0.67 | — | — | |
| SCHEMBL22993 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468635-B2 | Fused ring compound for use as mineralocorticoid receptor antagonist | KBP BIOSCIENCES CO., LTD. (CN) | 2016-10-18 | — | — | US | disclosed |
| US-9198902-B2 | 1,4-dihydropyridine-3,5-dicarboxylate derivatives and preparation and use thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2015-12-01 | — | — | US | disclosed |
| US-20150126501-A1 | Fused Ring Compound For Use As Mineralocorticoid Receptor Antagonist | NOVO NORDISK A/S (DK) | 2015-05-07 | — | — | US | disclosed |
| US-8946279-B2 | Fused ring compound for use as mineralocorticoid receptor antagonist | KBP BIOSCIENCES CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| EP-2703398-A1 | 1,4-DIHYDROPYRIDINE -3,5-DICARBOXYLATE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2014-03-05 | — | — | EP | disclosed |
| US-20140045896-A1 | 1,4-dihydropyridine-3,5-dicarboxylate Derivatives And Preparation And Use Thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2014-02-13 | — | — | US | disclosed |
| US-20130289029-A1 | Fused Ring Compound For Use As Mineralocorticoid Receptor Antagonist | NOVO NORDISK A/S (DK) | 2013-10-31 | — | — | US | disclosed |
| EP-2607363-A1 | FUSED RING COMPOUND FOR USE AS MINERALOCORTICOID RECEPTOR ANTAGONIST | KBP Biosciences Co., Ltd. (CN) | 2013-06-26 | — | — | EP | disclosed |