Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048932 | 1.00 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL1787506 | 1.00 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL1786199 | 0.80 | SIGMAR1 (0.37) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL3104162 | 0.78 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL11532068 | 0.78 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL2008948 | 0.77 | GBA1 (0.38) | SIGMAR1 | |
| SCHEMBL6780999 | 0.76 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL3718838 | 0.76 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL2349160 | 0.76 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL293973 | 0.76 | BIRC2 (0.46) | CYP2C19CYP1A2ALOX15CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |