Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736300 | 0.87 | FAAH (0.64) | FAAHF10GRIN2BMMP13MMP14 | |
| SCHEMBL1532790 | 0.85 | FAAH (0.68) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL15048972 | 0.85 | FAAH (0.62) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL29976154 | 0.83 | FAAH (0.62) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL1532715 | 0.83 | FAAH (0.62) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL12736284 | 0.83 | FAAH (0.62) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL12736299 | 0.82 | FAAH (0.63) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL16333042 | 0.79 | FAAH (0.61) | FAAHMMP13MMP14MAOBMAOA | |
| SCHEMBL1532895 | 0.78 | FAAH (0.58) | FAAHF10NR4A2GRIN2BMMP13 | |
| SCHEMBL1532894 | 0.78 | FAAH (0.58) | FAAHF10NR4A2GRIN2BMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607362-A1 | Piperidine and piperazine carboxylates as FAAH inhibitors | Astellas Pharma Inc. (JP) | 2013-06-26 | — | — | EP | disclosed |