Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049657 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A4LMNAKDM4EALDH1A1 | |
| Lactic Acid SCHEMBL4337806 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4KDM4EALDH1A1TP53 | |
| SCHEMBL28302159 | 0.80 | SSTR4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1206581 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4KDM4EALDH1A1SLC6A3 | |
| Hydrochloric Acid SCHEMBL17111268 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4KDM4EALDH1A1SLC6A3 | |
| Hydrochloric Acid SCHEMBL31293114 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4KDM4EALDH1A1SLC6A3 | |
| SCHEMBL25371901 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7299084 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23929455 | 0.76 | — | — | |
| SCHEMBL10505054 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4KDM4ESLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140322302-A1 | THERAPEUTIC PEPTIDES | COMBIMAB, INC (US) | 2014-10-30 | — | — | US | disclosed |
| US-8748575-B2 | Therapeutic peptides | COMBIMAB, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20140038881-A1 | Therapeutic Peptides | COMBIMAB, INC (US) | 2014-02-06 | — | — | US | disclosed |
| EP-2605786-A2 | THERAPEUTIC PEPTIDES | Combimab, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2011156453-A2 | THERAPEUTIC PEPTIDES | COMBIMAB, INC. (US) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322302-A1 | THERAPEUTIC PEPTIDES | VIP, GMPS, PDE3A | SLC6A2 3688/4885SLC6A4 3484/4885LMNA 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.