Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185652 | 0.86 | — | — | |
| Lactic Acid SCHEMBL8196431 | 0.85 | SLC6A2 (0.35) | SLC6A2SLC6A4TP53SLC6A3MLNR | |
| Propionamide SCHEMBL27586347 | 0.83 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| Ethylene Glycol SCHEMBL10850449 | 0.81 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| Lactic Acid SCHEMBL27538299 | 0.80 | TP53 (0.38) | SLC6A2SLC6A4TP53 | |
| Morpholine SCHEMBL5147041 | 0.80 | MEN1 (0.39) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL1206581 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL15049657 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4TP53SLC6A3KDM4E | |
| SCHEMBL15049656 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4TP53SLC6A3KDM4E | |
| Lactic Acid SCHEMBL25180586 | 0.78 | TP53 (0.39) | SLC6A2SLC6A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024478-A1 | AQUEOUS LAUNDRY DETERGENT COMPOSITIONS HAVING IMPROVED SOFTENING AND ANTISTATIC PROPERTIES | Akzo Nobel N.V. (NL) | 2009-02-18 | — | — | EP | claimed |
| WO-2008000333-A1 | AQUEOUS LAUNDRY DETERGENT COMPOSITIONS HAVING IMPROVED SOFTENING AND ANTISTATIC PROPERTIES | AKZO NOBEL N.V. (NL) | 2008-01-03 | — | — | WO | claimed |