Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049781 | 0.90 | MAOB (0.32) | MAOBALDH1A1MEN1MAPTHTT | |
| SCHEMBL15049857 | 0.90 | ABCB1 (0.30) | — | |
| SCHEMBL15049741 | 0.88 | — | — | |
| SCHEMBL15049814 | 0.88 | KCNJ1 (0.30) | — | |
| SCHEMBL3011529 | 0.77 | KIF11 (0.45) | — | |
| SCHEMBL15049780 | 0.75 | MAOB (0.34) | MAOBALDH1A1MEN1LMNAMAPT | |
| SCHEMBL3017342 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15049881 | 0.74 | MAOB (0.34) | MAOBALDH1A1MEN1KMT2A | |
| SCHEMBL15049784 | 0.74 | MAOB (0.34) | MAOBALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL15049811 | 0.74 | NR3C2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2179994-B1 | FUSED BICYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-26 | — | — | EP | claimed |