Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505034 | 1.00 | CYP2D6 (0.48) | CYP2D6ADAM17HDAC4HDAC1ALDH1A1 | |
| SCHEMBL10276327 | 0.89 | ADAM17 (0.57) | CYP2D6ADAM17HDAC4HDAC1ALDH1A1 | |
| SCHEMBL10276320 | 0.89 | ADAM17 (0.57) | CYP2D6ADAM17HDAC4HDAC1ALDH1A1 | |
| SCHEMBL10476316 | 0.86 | ADAM17 (0.48) | CYP2D6ADAM17HDAC4HDAC1ALDH1A1 | |
| SCHEMBL10476319 | 0.86 | ADAM17 (0.48) | CYP2D6ADAM17HDAC4HDAC1ALDH1A1 | |
| SCHEMBL10475842 | 0.74 | ADAM17 (0.55) | ADAM17ALDH1A1KDM4EMAPT | |
| SCHEMBL10475882 | 0.74 | ADAM17 (0.55) | ADAM17ALDH1A1KDM4EMAPT | |
| SCHEMBL10275951 | 0.73 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL10275940 | 0.73 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL10275880 | 0.72 | ADAM17 (0.44) | ADAM17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033009-A1 | N- [2-HYDROXYCARBAMOYL-2- (PIPERAZINYL) ETHYL] BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-03-24 | — | — | WO | disclosed |