Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.88 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | DGKA | P23743 | 2/20 | 0.74 |
| ▸ | CNR2 | P34972 | 4/20 | 0.63 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 2/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.58 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetyl Palmitate SCHEMBL6241713 | 1.00 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16932038 | 1.00 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL10727472 | 1.00 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL4098514 | 1.00 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL4989747 | 0.98 | KDM4E (0.85) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerol Monolaurate SCHEMBL18000733 | 0.97 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycol Distearate SCHEMBL3710636 | 0.95 | KDM4E (0.90) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL9576820 | 0.95 | KDM4E (0.79) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Octane SCHEMBL5181039 | 0.94 | LMNA (1.00) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL5719482 | 0.94 | LMNA (1.00) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473195-A2 | GASTRIC RETENTIVE PHARMACEUTICAL COMPOSITIONS FOR IMMEDIATE AND EXTENDED RELEASE OF ACETAMINOPHEN | Depomed, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026125-A2 | GASTRIC RETENTIVE PHARMACEUTICAL COMPOSITIONS FOR IMMEDIATE AND EXTENDED RELEASE OF ACETAMINOPHEN | DEPOMED, INC. (US) | 2011-03-03 | — | — | WO | disclosed |