Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651074 | 0.80 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL29651058 | 0.80 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL70712 | 0.80 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL3598042 | 0.78 | MAPK1 (0.67) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL29508473 | 0.78 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL69747 | 0.78 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL64763 | 0.78 | MAPK1 (0.67) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL30574349 | 0.78 | MAPK1 (0.67) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL64688 | 0.78 | MAPK1 (0.67) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL1755302 | 0.77 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112352-A1 | OPIOID RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2017-01-04 | — | — | EP | claimed |
| EP-1725537-B1 | NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-07-13 | — | — | EP | claimed |
| CN-1950342-A | Novel compounds as opioid receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2007-04-18 | — | — | CN | claimed |
| EP-3112352-B1 | OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-11-21 | — | — | EP | disclosed |
| EP-2952096-B1 | Amide compound, an arthropod pest control agent and a method for controlling arthropod pest | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9814235-B2 | Method for controlling arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-14 | — | — | US | disclosed |
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| EP-3112352-A1 | OPIOID RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2017-01-04 | — | — | EP | disclosed |
| EP-2653465-B1 | Opioid receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-13 | — | — | EP | disclosed |
| EP-2952096-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | Sumitomo Chemical Company, Limited (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2653465-A1 | Opioid receptor modulators | Janssen Pharmaceutica NV (BE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2298744-B1 | Opioid receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2573068-A1 | Process for preparing intermediates of compounds useful as opioid receptor modulators | Janssen Pharmaceutica NV (BE) | 2013-03-27 | — | — | EP | disclosed |
| EP-1725537-B1 | NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-07-13 | — | — | EP | disclosed |
| EP-2298744-A2 | Opioid receptor modulators | Janssen Pharmaceutica NV (BE) | 2011-03-23 | — | — | EP | disclosed |
| CN-1351646-A | Composition and method for bleaching a substrate | UNILEVER PLC (NL) | 2002-05-29 | — | — | CN | disclosed |
| US-4812454-A | Nitromethylene derivatives and their use as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4772620-A | MITICIDES, PARASITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0212600-A2 | Nitromethylene derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344466-A1 | METHOD FOR CONTROLLING ARTHROPOD PEST | H1-0, H1-3, H1-2 | MAPK1 2419/4885KDM4E 1006/4885L3MBTL1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.