Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508473 | 1.00 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL14234693 | 0.89 | MAPK1 (0.80) | MAPK1KDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL29826109 | 0.89 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL64700 | 0.89 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1P4HA1MIF | |
| SCHEMBL423045 | 0.89 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL989398 | 0.89 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL64024 | 0.89 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL1019173 | 0.87 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL8251331 | 0.87 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1CA1CA2 | |
| SCHEMBL30401004 | 0.87 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3654929-B1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | OREAL (FR) | 2024-05-29 | — | — | EP | claimed |
| CN-116943730-A | Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound | 浙江大学 | 2023-10-27 | — | — | CN | claimed |
| EP-3654929-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2020-05-27 | — | — | EP | claimed |
| EP-3236919-B1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | OREAL (FR) | 2019-10-16 | — | — | EP | claimed |
| EP-2861206-B1 | COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR | OREAL (FR) | 2019-06-12 | — | — | EP | claimed |
| WO-2019016153-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2019-01-24 | — | — | WO | claimed |
| EP-3386476-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2018-10-17 | — | — | EP | claimed |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2018-05-31 | — | — | US | claimed |
| EP-3307901-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | Biome Bioplastics Limited (GB) | 2018-04-18 | — | — | EP | claimed |
| US-20180000712-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | L'OREAL (FR) | 2018-01-04 | — | — | US | claimed |
| CN-107106452-A | Specific pyridinedicarboxylicacid acid derivatives/antioxidant combination | 欧莱雅 | 2017-08-29 | — | — | CN | claimed |
| WO-2017097849-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2017-06-15 | — | — | WO | claimed |
| WO-2016202875-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2016-12-22 | — | — | WO | claimed |
| US-9107847-B2 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | SOCIETE L'OREAL S.A. (FR) | 2015-08-18 | — | — | US | claimed |
| EP-1352629-B1 | Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss | OREAL (FR) | 2011-06-22 | — | — | EP | claimed |
| US-20030223945-A1 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | SOCIETE L'OREAL S.A. (FR) | 2003-12-04 | — | — | US | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| EP-0403627-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000712-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | GPX4, PRDX3, DPYD | MAPK1 1897/4885KDM4E 1900/4885L3MBTL1 4390/4885 |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | MAPK1 2904/4885KDM4E 657/4885L3MBTL1 4344/4885 |
| US-20030223945-A1 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | KRT18, AKR1C3, MC1R | MAPK1 162/4885KDM4E 1534/4885L3MBTL1 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.