Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15053213 | 1.00 | LMNA (0.34) | LMNADNM1HSP90AA1HTTPLA2G1B | |
| Bromide SCHEMBL15053511 | 1.00 | LMNA (0.34) | LMNADNM1HSP90AA1HTTPLA2G1B | |
| SCHEMBL367893 | 0.98 | LMNA (0.35) | LMNADNM1HTTMAPTCYP2D6 | |
| Bromide SCHEMBL650551 | 0.98 | LMNA (0.31) | LMNA | |
| Iodide SCHEMBL15008381 | 0.97 | LMNA (0.34) | LMNAHTTSMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL15052946 | 0.97 | LMNA (0.34) | LMNAHTTKMT2ASMN1; SMN2RAD52 | |
| Iodide SCHEMBL15053220 | 0.97 | LMNA (0.34) | LMNAHTTSMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL2293581 | 0.97 | LMNA (0.34) | LMNAHTTKMT2ASMN1; SMN2RAD52 | |
| Iodide SCHEMBL15008594 | 0.97 | LMNA (0.34) | LMNAHTTSMN1; SMN2MAPTNPC1 | |
| Iodide SCHEMBL15008815 | 0.97 | LMNA (0.34) | LMNAHTTSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615632-B1 | MICROSTRUCTURE MANUFACTURING METHOD USING TREATMENT LIQUID FOR INHIBITING PATTERN COLLAPSE IN MICROSTRUCTURES | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-8980812-B2 | Treatment liquid for inhibiting pattern collapse in microstructures, and microstructure manufacturing method using said treatment liquid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2615632-A1 | TREATMENT LIQUID FOR INHIBITING PATTERN COLLAPSE IN MICROSTRUCTURES, AND MICROSTRUCTURE MANUFACTURING METHOD USING SAID TREATMENT LIQUID | Mitsubishi Gas Chemical Company, Inc. (JP) | 2013-07-17 | — | — | EP | disclosed |
| US-20130165365-A1 | TREATMENT LIQUID FOR INHIBITING PATTERN COLLAPSE IN MICROSTRUCTURES, AND MICROSTRUCTURE MANUFACTURING METHOD USING SAID TREATMENT LIQUID | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-06-27 | — | — | US | disclosed |