Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15053680 | 0.91 | DHODH (0.59) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10861648 | 0.89 | DHODH (0.67) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14066640 | 0.88 | DHODH (0.65) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL21050681 | 0.85 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10861643 | 0.84 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL3944683 | 0.84 | DHODH (0.60) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL13930268 | 0.84 | DHODH (0.63) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15054443 | 0.83 | DHODH (0.59) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11389721 | 0.83 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 | |
| SCHEMBL29705221 | 0.83 | DHODH (0.62) | DHODHNPSR1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |