Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301210 | 1.00 | MAPK1 (0.40) | MAPK1ALDH1A1PDE4BBRD4MMP2 | |
| SCHEMBL994649 | 0.88 | BRD4 (0.44) | MAPK1ALDH1A1BRD4MMP2ANPEP | |
| SCHEMBL15684230 | 0.88 | BRD4 (0.44) | MAPK1ALDH1A1BRD4MMP2ANPEP | |
| SCHEMBL3048242 | 0.88 | BRD4 (0.44) | MAPK1ALDH1A1BRD4MMP2ANPEP | |
| SCHEMBL7858138 | 0.88 | BRD4 (0.44) | MAPK1ALDH1A1BRD4MMP2ANPEP | |
| SCHEMBL2372196 | 0.88 | BRD4 (0.44) | MAPK1ALDH1A1BRD4MMP2ANPEP | |
| SCHEMBL3431419 | 0.85 | MAPK1 (0.40) | MAPK1ALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL6159675 | 0.84 | DGAT1 (0.41) | MAPK1PDE4BDGAT1 | |
| SCHEMBL6159678 | 0.84 | DGAT1 (0.41) | MAPK1PDE4BDGAT1 | |
| SCHEMBL6160832 | 0.84 | DGAT1 (0.41) | MAPK1PDE4BDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |