Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664523 | 0.88 | GAA (0.55) | MAPTSMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL54627 | 0.88 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL5708190 | 0.88 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2ALDH1A1HTTKDM4E | |
| Hydrogen Sulfide SCHEMBL29443442 | 0.86 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL1792981 | 0.85 | KMT2A (0.51) | MAPTSMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL16952869 | 0.83 | MEN1 (0.46) | MAPTSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL1817014 | 0.82 | CA12 (0.60) | MAPTSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL9739370 | 0.81 | HTT (0.46) | MAPTALDH1A1HTTLMNAALOX5 | |
| SCHEMBL16958102 | 0.78 | NPC1 (0.42) | MAPTSMN1; SMN2ALDH1A1HTTALOX5 | |
| SCHEMBL16950559 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |