Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588340 | 0.89 | TSHR (0.59) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL28330166 | 0.87 | MEN1 (0.41) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10174909 | 0.87 | CHRNB4 (0.45) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16957626 | 0.87 | MEN1 (0.41) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10174929 | 0.87 | MEN1 (0.43) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL31413307 | 0.87 | CHRNB4 (0.45) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL14017959 | 0.84 | ALDH1A3 (0.47) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16952871 | 0.84 | MEN1 (0.40) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16952869 | 0.84 | MEN1 (0.46) | HTTMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16960810 | 0.83 | MAPT (0.42) | HTTMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006956-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1992-04-30 | — | — | WO | disclosed |