Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622343 | 0.83 | SLC2A1 (0.50) | SLC2A1PIM1PIM2TTKNNMT | |
| SCHEMBL15054260 | 0.83 | SLC2A1 (0.47) | SLC2A1PIM1PIM2TTKNNMT | |
| SCHEMBL28489879 | 0.79 | HAVCR2 (0.44) | SLC2A1NNMTMEN1KMT2AAURKA | |
| SCHEMBL28486421 | 0.77 | BTK (0.38) | SLC2A1NNMTAURKARPS6KB1DGAT1 | |
| SCHEMBL17646064 | 0.77 | SLC2A1 (0.50) | SLC2A1PIM1PIM2TTKNNMT | |
| SCHEMBL15054611 | 0.74 | KDM4E (0.41) | KMT2AHAVCR2 | |
| SCHEMBL2483995 | 0.74 | NPSR1 (0.50) | SLC2A1PIM1PIM2TTKNNMT | |
| SCHEMBL7079605 | 0.72 | HAVCR2 (0.42) | MEN1KMT2AHAVCR2 | |
| SCHEMBL17241448 | 0.71 | CSF1R (0.40) | SLC2A1NNMTDGAT1CSF1R | |
| SCHEMBL19877026 | 0.71 | CYP11B2 (0.36) | LCKRPS6KB1KDRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |