Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330192 | 0.87 | ABL1 (0.49) | ABL1RIN1CA12CA1CA2 | |
| SCHEMBL15528472 | 0.83 | CA1 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6066541 | 0.80 | CA1 (0.57) | ABL1RIN1CA12CA1CA2 | |
| SCHEMBL21383989 | 0.79 | ABL1 (0.43) | ABL1RIN1CA12CA1CA2 | |
| SCHEMBL26306813 | 0.76 | ABL1 (0.42) | ABL1RIN1CA12CA1CA2 | |
| SCHEMBL1505672 | 0.75 | KDM4E (0.50) | CA1CA2CA9MAPTKDM4E | |
| SCHEMBL4741678 | 0.75 | ATM (0.44) | ALDH1A1 | |
| Methyl 3,5-Dibromobenzoate SCHEMBL2408987 | 0.74 | NOTUM (0.67) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL184614 | 0.74 | NOTUM (0.67) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL27092721 | 0.72 | HPGD (0.47) | MAPTTDP1LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048876-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-17 | — | — | US | disclosed |
| US-11213032-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-04 | — | — | US | disclosed |
| EP-3856715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-08-04 | — | — | EP | disclosed |
| US-10869477-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-22 | — | — | US | disclosed |
| WO-2020064564-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-02 | — | — | WO | disclosed |
| US-20200037613-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-06 | — | — | US | disclosed |
| EP-3601275-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| EP-3601280-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031817-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-30 | — | — | US | disclosed |
| WO-2019243263-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-26 | — | — | WO | disclosed |
| WO-2011101229-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011024004-A1 | HETEROCYCLIC UREA DERIVATIVES USEFUL FOR TREATMENT OF BACTERIAL INFECTION | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011024004-A1 | HETEROCYCLIC UREA DERIVATIVES USEFUL FOR TREATMENT OF BACTERIAL INFECTION | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| EP-2262801-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | AstraZeneca AB (SE) | 2010-12-22 | — | — | EP | disclosed |
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| WO-2009106885-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106885-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| CN-1882568-A | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-12-20 | — | — | CN | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | NOTUM 1133/4885ABL1 1988/4885RIN1 1325/4885 |
| US-10869477-B2 | Insecticidal compounds | CBR3, C1R, C1S | NOTUM 1481/4885ABL1 759/4885RIN1 1621/4885 |
| US-11213032-B2 | Insecticidal compounds | DDT, ACHE, CYP2E1 | NOTUM 684/4885ABL1 571/4885RIN1 1197/4885 |
| US-20200037613-A1 | INSECTICIDAL COMPOUNDS | DDT, ACHE, CYP2E1 | NOTUM 692/4885ABL1 617/4885RIN1 1121/4885 |
| US-20200031817-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | NOTUM 2016/4885ABL1 2101/4885RIN1 487/4885 |
| US-20220048876-A1 | INSECTICIDAL COMPOUNDS | DDT, ACHE, CYP2E1 | NOTUM 558/4885ABL1 750/4885RIN1 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.