Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544690 | 0.80 | GAA (0.55) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL2544692 | 0.80 | GAA (0.55) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL27622633 | 0.74 | MAPT (0.52) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL2532833 | 0.73 | CA1 (0.71) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL2532836 | 0.73 | CA1 (0.71) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL11253873 | 0.73 | MAPT (0.57) | GAARAB9AMAPTKMT2APOLB | |
| SCHEMBL6258679 | 0.73 | SMN1; SMN2 (0.51) | GAARAB9AMAPTKMT2APOLB | |
| SCHEMBL3269740 | 0.72 | GAA (0.50) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL27905231 | 0.72 | MEN1 (0.55) | GAARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL15073446 | 0.72 | NOS3 (0.50) | GAARAB9AMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |